Senin, 03 Agustus 2020

Reopening schools WILL cause a second Covid-19 wave unless test and trace improves - Daily Mail

Reopening schools in September WILL lead to a catastrophic second wave of coronavirus unless NHS test and trace drastically improves, major study claims

  • Reopening schools could result in another crisis peaking in December
  • But it could be avoided if testing dramatically ramps up to reach 75% of cases
  • And the NHS contact tracing system would need to reach 68% of people
  • But scientists say the current NHS system is 'not good enough' 
  • Other measures to 'mitigate' the effects of schools would be needed

Children returning to school in September will trigger a devastating second wave of Covid-19 that could infect twice as many as the first unless the test and trace system drastically improves, a major study has claimed.

Scientists said reopening schools in the UK would inevitably result in another crisis that peaks in December. 

But it could be avoided — with pubs remaining open and no draconian lockdowns needed — if testing is dramatically ramped up and the contact tracing system becomes better. 

Three quarters of people with Covid-19 would need to be tested and self-isolate to prevent a second wave caused by schools reopening.

Experts found that, to prevent a second wave when schools reopen, the NHS contact tracing system must reach 68 per cent of cases and their contacts.  

But the current NHS system is 'not good enough'. It reaches half of contacts and only a fraction of symptomatic cases are tested, according to researchers from University College London and the London School of Hygiene and Tropical Medicine. 

The authors said without improvements in testing it will be 'absolutely essential' to introduce other measures in September to 'mitigate' the effects of schools opening. This could mean pubs are forced to shut or greater restrictions are placed on people meeting indoors.  

England's chief medical officer last week admitted the UK may have reached a limit for how much society can be opened up safely, without leading to a resurgence of the virus. 

One scientist who advises the government even suggested closing pubs as a trade-off for allowing schools to finally open again.

Experts found that, to prevent a second wave when schools reopen, the NHS contact tracing system must reach 68 per cent of cases and their contacts. But as well as that, three quarters of people with Covid-19 would need to be tested and self-isolate (bottom, the measures combined showing a second 'wave' would not occur)

Experts found that, to prevent a second wave when schools reopen, the NHS contact tracing system must reach 68 per cent of cases and their contacts. But as well as that, three quarters of people with Covid-19 would need to be tested and self-isolate (bottom, the measures combined showing a second 'wave' would not occur)

Another study also published today suggested that schools could re-open safely but only under strict rules and with robust contact tracing.

The research looked at how Covid-19 spread in schools in Australia, one of the only countries to keep its schools open during the pandemic.

It found that outbreaks were not common in schools and children do not spread the coronavirus as much as adults do. Separate scientific research has found exactly the opposite.  

Schools in England, Wales and Northern Ireland are planned to return in September, while Scotland's first term begins at a slightly later date than usual on August 11. 

SHOULD PUBS CLOSE FOR SCHOOLS TO OPEN? 

The study comes after one scientist suggested that pubs may need to shut to allow schools to reopen.

Professor Graham Medley told the BBC on Sunday there may need to be a 'trade-off', with the reopening of schools seen as a 'priority' for children's wellbeing. 

Professor Medley, a member of the Scientific Advisory Group for Emergencies (Sage), said England could have to consider closing pubs in order to reopen schools next month.

When asked about the chief medical officer Professor Chris Whitty's prediction that the country was 'near the limits' of opening up society, the London School of Hygiene and Tropical Medicine academic told BBC Radio 4's Today programme: 'I think that's quite possible.

'I think we're in a situation whereby most people think that opening schools is a priority for the health and wellbeing of children and that when we do that we are going to reconnect lots of households.

'And so actually, closing some of the other networks, some of the other activities may well be required to enable us to open schools.

'It might come down to a question of which do you trade off against each other and then that's a matter of prioritising, do we think pubs are more important than schools?'

He claimed he thought it was 'highly unlikely' that restrictions imposed on the north-west of England last week would be 'the last intervention that has to be done regionally', adding: 'I fully expect there will have to be others in different places at different times.'

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But as cases of Covid-19 rise in the UK, there are concerns school start-dates will be delayed. The easing of some lockdown restrictions were set back on August 1.

Professor Chris Whitty, England's CMO, said on Friday the UK has probably reached a limit for how much of society can be opened up safely just weeks before schools are supposed to return.

Today researchers at UCL working with a team at LSHTM revealed that, if schools do re-open and lockdown is gradually lifted with more people slowly returning to work, a second wave will occur. 

The secondary wave would result in the R rate — the number of people each Covid-19 patient infects — rising above the dreaded number of one.

This could yield a secondary wave of infections 2-2.3 times the size of the first, which has so far killed around 46,201 people.

The peak would come in December, or in February 2021 if schools re-open on just a part-time basis.

Dr Jasmina Panovska-Griffiths, study author, said: 'Our results are reflective of a broader loosening of lockdown, rather than the effects of transmission within schools exclusively.'

The study, published today in The Lancet Child and Adolescent Health, assumed children were as infectious as adults. 

But the results remained true even when the team re-ran the model with the assumption that children and young people were 50 per cent as infectious as adults.

Commenting on the study, Matt Keeling, professor of populations and disease at University of Warwick, said: 'In essence the problem is simple.

'Reopening schools is going to increase the R number so if we are to keep R below 1 and prevent a second wave, some other forms of control are necessary.

'The reopening of schools should clearly be a key priority for the UK, many children will have gone over 5 months without setting foot in a classroom. 

'The key questions are how much impact will school reopening have on the epidemic and what can be done to mitigate this.'

The study found a second wave could be prevented, however, if a robust testing and an adequate contact tracing system was in place.

Both have come under intense scrutiny in the UK, with test and trace performance figures in England worsening last week.

The study said testing would need to be ramped up so between 59 per cent and 87 per cent of symptomatic patients are tested during the infectious period.

It is not clear how many symptomatic patients in the UK are tested each day. 

But one of the study authors, Chris Bonell, professor of public health sociology at LSHTM, said: 'It looks from the ONS data like there are about 4,200 new infections per day. 

'And it looks like from the testing data there are about 4,200 testing positive per week. So it looks like about one in seven (14 per cent). So, that's not good enough, basically.'

The study said 75 per cent of individuals with symptomatic infection would need to be diagnosed and isolated if schools return full-time in September. It dips to 65 per cent if schools run on a part-time rota system. 

This is based on the contact tracing system reaching 68 per cent of people — a combination of 75 per cent of positive Covid-19 cases and 90 per cent of their contacts.

The NHS is currently reaching an overall standard of 50 per cent, Professor Bonell claims.

'Currently, test, trace, isolating (TTI) is not achieving the levels that we modelled. Looking at the NHS reports from the TTI system, it looks like it's about 50 per cent coverage.'

He added: 'The most recent data [shows] about 81 per cent of positives are interviewed, about 81 per cent of those report contacts and about 75 per cent of those contacts are reached so overall that equates to coverage of 50 per cent.'

If only 40 per cent of contacts could be traced, under a more pessimistic tracing scenario, testing would need to increase to a higher 87 per cent if school returned full time. 

Professor Bonell said: 'Our study should not be used to keep schools shut because of a fear of a second wave but as a loud call to action to improve the infection control measures and test and trace system so we can get children back to school.'

The study said 75 per cent of individuals with symptomatic infection would need to be diagnosed and isolated if schools return full-time in September to avoid a second wave (graph on left, middle row). This is based on the contact tracing system reaching 68 per cent of people. The findings for a partial opening of school is shown on the right

The study said 75 per cent of individuals with symptomatic infection would need to be diagnosed and isolated if schools return full-time in September to avoid a second wave (graph on left, middle row). This is based on the contact tracing system reaching 68 per cent of people. The findings for a partial opening of school is shown on the right

The study shows that even with contact tracing, testing needs to be ramped up in order to reduce cases and deaths. The top graphs show how deaths would increase if testing only reaches 18 per cent of symptomatic cases

The study shows that even with contact tracing, testing needs to be ramped up in order to reduce cases and deaths. The top graphs show how deaths would increase if testing only reaches 18 per cent of symptomatic cases

Professor Bonell suggested that other sectors will face new restrictions in September unless the coverage reached by NHS Test & Trace improves.

IS THE TEST AND TRACE SCHEME GETTING WORSE? 

Figures last week revealed some 4,242 people infected with coronavirus were referred to the test and trace scheme during the week of July 16-22.  

But just 2,809 (77 per cent) agreed to provide details of people they had come into close contact with recently, meaning thousands of potential patients went missed.

A total of 646 with the virus could not be reached at all by the tracers, who phone, text and email someone up to 10 times a day to get hold of them.

The contact tracing figures, released by the Department of Health, also found the programme failed to reach almost a fifth of people who tested positive for Covid-19 last week.

Little over 81 per cent of infected people were actually tracked down by tracers — marking the first time the system had caught more than 80 per cent of patients since it launched on May 28.

One in four people who came into close contact with someone infected with coronavirus could not be reached by the NHS Test and Trace service.

Only 75.1 per cent (13,974) of contacts were reached and asked to self-isolate. This was down from the 78.4 per cent reached in the previous week, and the 90.8 per cent reached in the first week of Test and Trace.

Scientists have previously said eight in 10 Covid-19 sufferers need to be reached and their contacts isolated for the system to be effective.

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He said: 'We're not giving specific recommendations about what sectors need to have restrictions imposed, but logically that is absolutely essential.'

It follows Professor Graham Medley, a top Government scientific adviser, suggesting on Sunday that pubs may need to shut when schools open.

Another study published in the same Lancet journal today also suggests schools in the UK can re-open safely — but only if stringent control measures are in place. 

Researchers identified all staff and children who attended a school or nursery in the Australian state of New South Wales while they had Covid-19.

Overall, 12 children and 15 adults were found to have attended schools or nurseries while infectious between 25 January to 10 April, when term ended.

All adults or the parents of children were interviewed at diagnosis to track who the cases had been in contact with during the time that they were infectious.  

Once contacts were identified, they were told to self isolate and were tested if they showed symptoms, allowing the authors to calculate how many secondary transmissions were linked with each primary case.

The team showed that, of the 633 close contacts who were tested following symptoms, 18 were found to have Covid-19.

It means that 1.2 per cent of all close contacts (1,448) got the coronavirus from a primary case.

However, some asymptomatic or milder cases may have been missed seeing as testing was only of those with tell-tale signs.

Further analysis of a subset of schools showed the transmission rate between staff (4.4 per cent) was much higher than between children (0.3 per cent), suggesting children do not spread the virus as much as adults.

The attack rate from child to staff was one per cent for child-to-staff, compared to 1.5 per cent the other way around.  

The researchers, led by Professor Kristine Macartney also said the transmission rates may have been higher in areas where contact tracing systems and testing were not as rigorous. 

In a linked commentary discussing both articles, Professor John Edmunds, a leading authority on mathematical modelling of the spread of infectious diseases at LSHTM, said: 'Both studies give potential options for keeping schools open and show the clear importance of adequate contact tracing and testing.' 

The UCL study modelled six different scenarios of school reopening using baseline data about how the coronavirus spreads.

Alongside school reopening, the model included the relaxation of measures across society, which they assumed would accompany one another.

For each scenario, they estimated the number of new infections and deaths, as well as the effective reproduction number.

As with any modelling study, a number of assumptions were made about the spread of the virus to measure the effects of lifting lockdown.

For example, it assumed the test used by Public Health England is 100 per cent accurate — however it is known this isn't the case. 

And the model assumes everyone tested gets their result within 24 hours, which official statistics show is not true either. 

In the UK, around three quarters of tests outside of hospitals are being returned in 24 hours, despite Prime Minister Boris Johnson setting a target of 100 per cent by the end of June. 

Dr Adam Kucharski, an associate professor in infectious disease epidemiology, LSHTM, said the model uses a 'very optimistic scenario about the speed and performance of testing'.

He added: 'In reality, there will be a trade off with speed and effectiveness – even if a high proportion of people ill with COVID-19 are tested, it won't stop transmission if test results end up taking too long or infected contacts aren't traced before they become infectious.'

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2020-08-03 22:30:55Z
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