Three people have died following a two-vehicle crash on the Dungannon Road near Cookstown, County Tyrone.
Police confirmed that the drivers of the vehicles - a woman in her 80s and a man in his 20s - and a woman in her 50s, who was a passenger in one of the cars, were killed.
It happened shortly after 15:30 GMT on Monday.
Four children and a woman in her 20s were also taken to the Royal Victoria Hospital where they remain.
The road between Killycolp Road and Annagh Road was closed for several hours but has since reopened.
The Northern Ireland Ambulance Service (NIAS) said it dispatched two rapid response paramedics, four emergency crews, one non-emergency crew, a hazardous area response team and an ambulance officer to the scene.
The Helicopter Emergency Medical Service (HEMS) Air Ambulance was tasked to the scene and the Northern Ireland Fire and Rescue Service (NIFRS) also attended.
Ch Supt Gerard Pollock appealed for information.
'The worst possible news'
Sinn Féin deputy leader Michelle O'Neill said it is "deeply tragic news".
"I offer my heartfelt sympathies to the families of those tragically killed and every best wish to those injured for a full and speedy recovery," she added.
Social Democratic and Labour Party (SDLP) MLA Patsy McGlone said it is "the worst possible news any family could receive but particularly at this time of year".
"My thoughts and prayers are with all those affected at this incredibly difficult time."
In a tweet, Ulster Unionist Party (UUP) leader Doug Beattie said: "I just can't imagine the horror those who survived have endured and the scene faced by the emergency services.
"Life is so precious and so fragile."
Democratic Unionist Party (DUP) leader Sir Jeffrey Donaldson said: "Our thoughts and prayers are with all involved in this tragic incident and the families and communities impacted by such a devastating loss.
"We also think of the emergency services who attended the scene and the health service staff caring for those injured."
Elsewhere, the M1 motorway has reopened in both directions between junction 15 at Dungannon and junction 14 at Tamnamore following an earlier crash.
There are no further details at present.
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2022-12-27 06:57:55Z
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