Rabu, 01 September 2021

Covid UK: Daily cases flatten at 35,693 positive tests amid fears schools' return will cause surge - Daily Mail

UK's daily Covid cases level off with 35,693 positive tests and infections drop again in England as hospital admissions fall by 2% - yet deaths reach highest level since MARCH because of bank holiday delay with 207 victims

  • England's Covid infections dipped by a tenth in a week, but experts fear they will surge as schools return
  • Cases in Scotland ticked up by around a quarter after children went back to the classroom in mid-August
  • It was claimed today that Britain's teenagers are yet to be offered jabs because it could disrupt booster doses

Britain's daily Covid cases have flattened off, official data revealed today amid growing fears the return of millions of schoolchildren in England will spark an uptick in cases.

Health chiefs posted another 35,693 infections across the UK as a whole, barely a change on the 35,847 recorded the previous week.

But England's infections fell again with Government data showing they were down by a tenth on last Wednesday. Yet in Scotland — which saw positive tests spiral to a record high after children returned to schools in mid-August — cases continued to rise. 

Covid hospitalisations also appear to have plateaued, with the latest data showing 842 people were admitted to wards across Britain on August 28, the most recent day figures are available for. In the previous week 859 people were hospitalised.

Another 207 deaths were recorded today in the highest daily toll since March when the second wave was running out of steam. The high numbers are mainly due to the bank holiday and its recording lag. 

With concerns mounting over the return of schools, teaching unions have called for secondary school pupils to wear face masks when they return to the classroom.  

There are fears infections among children could spill over into older people who studies suggest are more at risk from the virus.

But Britain is still yet to commit to a booster programme despite Israel having committed to one. Data suggests that the jabs have blunted their third wave barely two weeks after they were first rolled out. 

Pressure is growing on No10's advisers to sign off on a plan to dish out third doses to over-80s and vulnerable Brits — with ministers having hoped for the campaign to begin next Monday. 

ENGLAND: But England's infections fell again with Government data showing they were down by a tenth on last Wednesday

ENGLAND: But England's infections fell again with Government data showing they were down by a tenth on last Wednesday

SCOTLAND: Yet in Scotland — which saw positive tests spiral to a record high after children returned to schools in mid-August — cases continued to rise

SCOTLAND: Yet in Scotland — which saw positive tests spiral to a record high after children returned to schools in mid-August — cases continued to rise

Dr Mary Bousted, general secretary of the National Education Union, told the Daily Mirror that ministers needed to take urgent action to avoid disruption to the new academic year.

She said: 'It would be much better if schools had not been told to abandon measures which they adopted last term.

'At a time when infection levels are 26 times what they were this time last year, it makes no sense to go back into school with so few safety measures.' 

'We're going to see thousands of pupils and hundreds of teachers having to isolate,' she said. 'You only have to look at Scotland to see where we're heading.' 

Scale of long Covid in children 'nothing like' initially feared 

Up to one in seven children in England suffer from long Covid after recovering from the initial infection, according to the largest study of its kind.

The University College London research of almost 7,000 youngsters aged 11 to 17 found 14 per cent of those who tested positive for the virus had three or more persistent symptoms three months later.

The lead scientist behind the study said the problem of long Covid in children was 'not anything like' the scale warned about in previous reports.   

 

Only children who had a confirmed PCR test result were included in the research, unlike other studies, and they were compared to a control group.

Among the participants who were still feeling unwell three months after beating the virus, 7 per cent said they had five or more symptoms.

Common ailments included headaches and tiredness but there was no evidence that any of the children had 'severe' illness as a result of long Covid.

It comes amid a row over whether Britain should be routinely vaccinating secondary school pupils as classrooms go back and infections remain stubbornly high.

The topic has proven controversial because giving the jabs to children would be almost exclusively to protect adults from Covid. 

Children are at an extremely low risk of the virus itself but previous research suggested as many as half were struck down with long Covid, which some argued was another reason to vaccinate them.  

Yesterday Dr Bousted predicted that schools would be forced to adopt face masks and other Covid measures 'very shortly'.

Millions of youngsters in England, Wales and Northern Ireland are set to go back to classrooms between now and the end of next week, sparking fears of an inevitable spike in cases.

Pupils in England will only be required to test themselves twice a week for the virus, with all other measures including face masks and social distancing abandoned.

But in Scotland where schools returned in mid-August, pupils and staff are still required to wear face masks and keep a one-metre distance. Despite these measures the country has seen a record surge in Covid cases.

When 8.9million children in England went back last September it led to Covid cases spiking four-fold in a month. And they spilled over into older age groups, who are more vulnerable to the disease.

Schools in parts of the South West will still ask pupils to wear masks in corridors, playgrounds and 'communal areas' when they return.

And one school in Rotherham has pledged to defy Government guidance.

Wales High School in the South Yorkshire town will maintain masks and support bubbles when pupils return to the classroom this week.

Headteacher Pepe Di'Iasio told BBC Radio 4's Today programme yesterday: 'We're maintaining masks in crowded corridors, and in social areas because we feel that that will help keep the infection rates down.

'But we're also maintaining some of the pre-Covid rules of our one-way systems, and our separation of year groups that were formerly known as bubbles and they're now just going to be kept in new groups again to try and just keep crowds down and keep the numbers apart.' 

There is no national guidance on wearing masks in schools, with all the remaining restrictions dropped in May.

The bubble system, which saw pupils eat with the same group every day to stop the virus spreading, was also scrapped.

No10's Education Secretary has, however, said schools should consider keeping children in lunch 'bubbles' this term to improve behaviour.

Gavin Williamson is encouraging headteachers to extend the Covid measures because it has other benefits beyond restricting the virus.

But Mr Williamson said schools found it a great opportunity to teach 'family dining' – including table manners and social skills. 

Writing for the Mail, he also urged parents to encourage their children to get regularly tested and to ensure they don't get 'carried away'.

During the previous academic year schools were launched into Covid chaos with some sending whole year-groups home after just one positive test.

Official figures show that at the end of the last academic year 750,000 children had been sent home to self-isolate, despite there being only 40,000 positive tests.

Professor Eran Segal, a mathematician at the country's Weizmann Institute, tweeted today that hospitalisations had started to fall just two weeks after the top-up campaign started. This graph shows how Covid hospitalisations have started to level off in Israel just two weeks after its booster programme began. When the drive was started hospitalisations were doubling every week. Predictions suggested this would continue (green line). But just two weeks after the jabs were given out actual hospitalisations have slowed (blue line)

Professor Eran Segal, a mathematician at the country's Weizmann Institute, tweeted today that hospitalisations had started to fall just two weeks after the top-up campaign started. This graph shows how Covid hospitalisations have started to level off in Israel just two weeks after its booster programme began. When the drive was started hospitalisations were doubling every week. Predictions suggested this would continue (green line). But just two weeks after the jabs were given out actual hospitalisations have slowed (blue line)

There is a growing body of evidence that suggests Covid vaccine-triggered immunity wanes over time. Israel has seen its hospitalisations and Covid cases (pictured) start to fall barely two weeks after rolling out booster shots to over-60s. The country is now inviting everyone who has already been double-vaccinated for a third dose

There is a growing body of evidence that suggests Covid vaccine-triggered immunity wanes over time. Israel has seen its hospitalisations and Covid cases (pictured) start to fall barely two weeks after rolling out booster shots to over-60s. The country is now inviting everyone who has already been double-vaccinated for a third dose

Now WHO warns of threat of 'Mu' variant found in Colombia — and it has already been spotted in Britain 

World Health Organization bosses are now officially tracking another Covid variant named 'Mu'.

The mutant strain — which also has the scientific name B.1.621 — was first detected in Colombia in January.

Almost 4,000 cases have been spotted since then, and it has spread to more than 40 countries.

Nearly 50 cases of Mu have been spotted in Britain so far, and hundreds have been identified in the US.

The WHO's weekly bulletin claimed its mutations suggest it may be more resistant to vaccines, as was the case with the South African 'Beta' variant. There are fears it may be more infectious, too.

But the agency warned more studies would be needed to examine this further, with the WHO having now formally labelled Mu a 'variant of interest'.

Almost 4,000 cases of the variant have been detected to date since it first emerged in January, but the number of infections has fallen in recent weeks, coinciding with the rapid increase of the Delta variant. This graph shows the seven-day average proportion of cases that were due to the Mu variant worldwide. They reveal its prevalence has fallen recently

Almost 4,000 cases of the variant have been detected to date since it first emerged in January, but the number of infections has fallen in recent weeks, coinciding with the rapid increase of the Delta variant. This graph shows the seven-day average proportion of cases that were due to the Mu variant worldwide. They reveal its prevalence has fallen recently

The WHO report said: 'Since its first identification in Colombia in January 2021, there have been a few sporadic reports of cases of the Mu variant and some larger outbreaks have been reported from other countries in South America and in Europe.

'Although the global prevalence of the Mu variant among sequenced cases has declined and is currently below 0.1 per cent, the prevalence in Colombia (39 per cent) and Ecuador (13 per cent) has consistently increased.

'The epidemiology of the Mu variant in South America, particularly with the co-circulation of the Delta variant, will be monitored for changes.'

It came as No10 faced mounting pressure to launch a booster programme for over-80s and the immunocompromised.

Israel — which became the first country in the world to start offering boosters last month — started to see its hospitalisations level off just two weeks after handing out the extra doses. Its cases have also started to fall.

SIsrael started to offer over-60s — who are the most at risk of being hospitalised if they catch Covid — third jabs at the start of August. Last week it expanded the drive to everyone who's already had two doses. 

One of Britain's top Covid experts, Professor Paul Hunter, yesterday said he saw no reason 'whatsoever' why it had taken No10's advisers so long to sign off on booster dose plans. The infectious disease expert, from the University of East Anglia, called for over-80s and immunocompromised people to get their shots 'pretty soon'. 

But despite calls to hurry up and act before the next uptick in cases, the JCVI is still dithering over exactly who should be eligible for the third injections. 

A source close to the JCVI told The Independent that there was likely to be a surge in cases when schools returned.

But they insisted that it was not clear whether children should be vaccinated because the three jabs currently being deployed in Britain are less effective at stopping transmission.

The insider argued it was a complex decision whether to vaccinate younger children, who face a tiny risk of becoming seriously ill or dying if they get infected.

The UK's medical regulator — the MHRA — has already given the green light to administering the Pfizer and Moderna vaccines to over-12s.

But the Government's advisers have only so far allowed all over-16s to get jabs, with experts weighing up safety data before pressing ahead with the next step.

Fears have been raised over the very rare side-effect myocarditis, or inflammation of the heart, which is most common among young boys given the Pfizer jab. 

Ministers are keen to expand the roll-out to include over-12s, mirroring the programmes seen in other countries including the US and Israel. 

Some over-12s who suffer from medical conditions that put them at greater risk if they catch the virus or live with an adult that is vulnerable to Covid are already eligible to receive the vaccine.

But hundreds of families are still yet to get a first dose for their children, which ministers promised would be available for everyone before schools return this week and next.

Joe Jones, from Surrey, who suffers from a blood disorder, told BBC Radio 4's Today programme she had been unable to get a Covid vaccine for her young daughter because no clinic was set up in her area. 

She said: 'For the part of Surrey that I live in there are no clinics set up, so although the Government committed to inviting people to the clinics by 23 August they have not even set a date for the area that I live in.

'We can't just turn up and grab a jab, you have to be vaccinated at a specialist clinic that has a pediatrician on site.

She added: 'They committed to getting the children vaccinated before they go back to school, that is Monday for us, so that is not going to happen currently and it certainly wont have given her the two weeks to build any antibodies.'

Una Summerson, who works at charity Contact which has been helping parents struggling to secure Covid vaccines for their children, said families had been left 'going round in circles'.

University College London epidemiologist and SAGE member Professor Andrew Hayward told the programme Britain needed to be 'very careful' about how it rolled out booster shots.

'I think there is a case for vaccinating the most vulnerable again with booster doses,' he said.

'But that still leaves the UK massively over-ordered in terms of the amount of vaccines that it has, and still conservatively leaves somewhere between 100-200million doses that it could donate by the end of the year.'

Professor Hayward also called on Britain to help boost the vaccination drive around the world.

He said: 'If rich countries can’t sort out a problem like vaccinating the world, what hope have we got in pulling together to sort out a complex problem like climate change? 

'This really is an opportunity for global leadership. This is a relatively simple technical problem that can be solved with the political will and resource.'

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2021-09-01 15:34:06Z
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COVID-19: Scotland to require vaccine passports for nightclubs and large events, Nicola Sturgeon says - Sky News

Vaccine passports will be needed for entry to nightclubs and large-scale events in Scotland, Nicola Sturgeon has said.

The first minister told MSPs that the "limited use of vaccine certification" from later this month could help control the spread of COVID-19 through autumn and winter.

Numbers of new infections are 80% higher than last week and five times higher than four weeks ago, she said, describing the situation as "extremely concerning".

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COVID-19: Scotland cases double in a week

Rising hospital admissions also make the situation "fragile and serious", she added.

The new rules - if approved by parliament in a vote next week - will cover indoor live events with more than 500 unseated people, outdoor live events with more than 4,000 unseated, and any event with over 10,000 attendees.

Ms Sturgeon said that while activities covered by the scheme "matter to our economy, and to our cultural and social life", they are "not essential services" and bring "many people together in relatively small areas".

"By ensuring that people entering these settings are fully vaccinated, we would be taking a proportionate step to help make these settings safer for everyone attending and, by extension, for all of us," she said.

More on Covid-19

Time was key, she added: "For any decision of this nature to have an impact before winter, we would have to take and implement it quickly."

Vaccine passports are not being considered for the hospitality industry as a whole, and children and adults with certain medical conditions will be exempt.

From Friday, people in Scotland will be able to download a QR code showing their vaccine status.

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COVID-19: Booster jabs explained

Ms Sturgeon told parliament: "The Scottish government has made it clear that we do not believe that vaccination certification should ever be a requirement for any key services or in settings where people have no choice over attendance - for example, public transport, education, access to medical services or shops. We continue to hold to that position."

In England, there are plans to bring in vaccine passports to enter nightclubs and other "crowded venues" from the end of September.

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2021-09-01 15:33:45Z
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Afghans who helped British forces to be offered indefinite leave to remain in the UK - Sky News

Afghans who worked with the UK will be given indefinite leave to remain, the Home Office has announced.

People from Afghanistan who worked alongside the British government and army were previously only eligible for five years of temporary residency.

Now - as part of a scheme called Operation Warm Welcome - they will be able to stay in the UK permanently, giving them unrestricted rights to work.

The British government has sent troops back to Afghanistan to help evacuate British nationals, but Paul Farthing's wife and employee have not managed to board a flight
Image: Thousands of refugees who helped the UK in Afghanistan have arrived in Britain

The plan is available for those eligible for the Afghan Relocation and Assistance Policy (ARAP).

This prioritises those who were deemed to have a serious threat against their life now the Taliban controls Afghanistan.

More than 15,000 people have been evacuated from Afghanistan since 13 August, of which more than 8,300 are ARAP claimants.

All arrivals are also offered the COVID vaccine.

More on Afghanistan

More than 700 of those who have arrived in the UK are already jabbed and out of quarantine.

As well as the indefinite leave to remain, the UK government has said it will provide the following:

• £12m to help children with their education

• £3m to help people access healthcare

• £5m in housing support for councils

• Money for up to 300 undergraduate and postgraduate scholarships - with adults also able to access English language courses free of charge.

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Afghan refugees: Taliban 'would have killed us'

There will also be services to help new arrivals get National Insurance numbers, accommodation, and the creation of an online portal so offers of support can be registered.

Prime Minister Boris Johnson said: "We owe an immense debt to those who worked with the armed forces in Afghanistan and I am determined that we give them and their families the support they need to rebuild their lives here in the UK.

"I know this will be an incredibly daunting time, but I hope they will take heart from the wave of support and generosity already expressed by the British public."

The newly appointed Afghan Resettlement minister, Victoria Atkins, told Sky News: "Over the last two weeks alone we've evacuated some 15,000 people to our country and, of course, since April we've evacuated more people who have done right by us.

"They're the people who, on the ground over the last 20 years, have been working with our soldiers helping to protect them, helping to translate, helping to make our embassies and other areas work.

"So the prime minister's commitment is absolutely clear to this - they have done right by us, we want to do right by them."

The Afghan Citizens Resettlement Scheme is still being developed, with the aim of taking in up to 20,000 refugees from Afghanistan.

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2021-09-01 06:13:05Z
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Nicola Sturgeon to make covid statement as case numbers continue to rise across Scotland - Daily Record

Nicola Sturgeon is set to update the Scottish Parliament on the latest situation regarding the covid pandemic across the country.

The First Minister will address MSPs at Holyrood as cases of the deadly virus surge following the relaxation of the lockdown restrictions.

It will be Sturgeon 's first statement to the parliament since Scotland left the levels system on August 9, however she has held a number of media briefings in that time.

Due to the rise in cases there has been speculation that some restrictions could be reimposed in a bid to curb the surge.

However, it's not believed there will be any drastic changes due to the success of the vaccine rollout.

Here's all you need to know about the statement:

What time is the statement?

Nicola Sturgeon is expected to get to her feet in the Scottish Parliament just 2pm following portfolio questions in the Chamber.

She will deliver a statement to MSPs then take questions on the covid pandemic in Scotland.

Opposition and SNP/Green politicians will get to quiz the First Minister.

Where can I watch the statement?

The statement will be broadcast on the Scottish Parliament TV channel, it can be viewed here.

It can also be viewed on the Scottish Parliament official Facebook page.

The Daily Record will also show the update from Sturgeon on our main Facebook page.

If you're out and about or sitting at your desk then it can be followed on our live covid blog.

To sign up to the Daily Record Politics newsletter, click here.

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2021-09-01 03:30:00Z
52781848466183

Selasa, 31 Agustus 2021

NHS to roll out new cholesterol-lowering drug that 'could save 30,000 lives' - Sky News

Hundreds of thousands of people will soon have access to a cholesterol-lowering drug that could save 30,000 lives within the next decade, it has been announced.

The NHS will make the treatment available to 300,000 patients with high cholesterol and a history of cardiovascular disease over the next three years.

The number of people benefiting from the new medication, inclisiran, could rise to nearly half a million beyond that initial period, bosses say.

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August: NHS faces huge backlog in wake of pandemic

The drug, which could prevent about 55,000 heart attacks and strokes, is delivered as an injection twice a year and can be used alongside existing treatments like statins.

Heart disease is the world's biggest killer and accounts for a quarter of all deaths in England each year, claiming about 140,000 lives.

More than 40% of people in the nation have high cholesterol, which puts them at significant risk of developing heart disease.

About 6.5 million adults in England are currently taking drugs for the condition.

More on Drugs

Inclisiran will be administered as an injection in GP surgeries rather than hospitals to make it more convenient for patients.

After the first dose, the treatment will be given again after three months and then twice a year.

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June: Effect of lockdowns on life-saving treatment

Amanda Pritchard, chief executive of the NHS, said the rollout is part of the NHS's commitment to "using cutting-edge treatments to save and improve patients' lives".

"Heart disease is still one of the major killer conditions, so it is fantastic that we now have such an effective and convenient treatment for those living with dangerously high cholesterol levels," she said.

"This world-leading deal for the rollout of inclisiran will save lives and enable hundreds of thousands of people to benefit from this revolutionary treatment, while also being fair to taxpayers."

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May: NHS backlog leaves GP surgeries struggling

The treatment's rollout follows clinical trials that showed that the drug lowers the level of a type of fatty substance called LDL-C found in the blood by boosting the liver's ability to remove it.

High levels of LDL-C make people more likely to suffer a heart attack or stroke.

"Unprecedented" large quantities of the drug were secured in order to keep its cost "affordable", the NHS said.

Jules Payne, chief executive of HEART UK, welcomed the rollout, calling the medicine "an additional tool in the armour against cardiovascular disease".

"High cholesterol is very common and a major cause of cardiovascular disease, but the lack of symptoms means the first sign of the problem is often a heart attack," he added.

Health Secretary Sajid Javid said the "life-saving new treatment will make a difference to hundreds of thousands of people across England", and he added: "This is a huge step forward in tackling the scourge of heart disease, which tragically kills thousands every year."

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2021-08-31 23:52:52Z
52781851965575

Afghanistan: The questions facing Foreign Secretary Dominic Raab - BBC News

Dominic Raab
Reuters

On Wednesday, Foreign Secretary Dominic Raab will be grilled by the Foreign Affairs Committee over his handling of the UK's withdrawal from Afghanistan.

Here are some of the questions Mr Raab could face:

How many people have been left behind in Afghanistan?

Since April, more than 17,000 people have been evacuated from Afghanistan by the UK.

Around 5,000 were UK nationals, while the rest were mostly Afghans who worked for the British government, supported under the Afghanistan Relocation Assistance Policy (Arap).

Civilian evacuations came to an end at the weekend and Mr Raab has said it is difficult to ascertain how many people have been left behind, although he estimated that a few hundred British nationals still remain in the country.

Last week, Defence Secretary Ben Wallace said there were around 800 to 1,100 Afghans eligible to come to the UK under the Arap scheme who would not be able to make it out of the country.

Mr Raab dismissed claims from MPs that there could be as many as 7,000 Arap-eligible applicants left behind.

The foreign secretary can expect MPs to push him on the most recent figures.

What will happen to Afghans trying to leave the country?

Kabul Airport
Reuters

In addition to the Arap scheme, the UK says its Afghan Citizens' Resettlement Scheme aims to allow 5,000 Afghans to settle in the UK, with the long-term goal a total of 20,000.

However, with the UK's airlift evacuations at an end, those hoping to leave may have to resort to escaping into neighbouring countries by land.

These journeys could be dangerous and would entail passing through Taliban checkpoints.

There is also no guarantee bordering countries would be willing to let in Afghan refugees or that the Taliban would let people leave.

Given the UK no longer has a diplomatic presence in Afghanistan, will it struggle to process resettlement claims from Afghans?

The UK has suggested it will try to process resettlement claims in neighbouring countries but will people have to risk making a potentially dangerous journey out of Afghanistan before they know if they are eligible to move to the UK?

Does the UK have deals with countries neighbouring Afghanistan?

The German Foreign Minister, Heiko Mass, has just completed a visit to the region taking in Turkey, Uzbekistan, Tajikistan, Pakistan and Qatar.

Germany says Uzbekistan has agreed to allow those identified to be at-risk to be flown in and on to Germany once flights restart from Kabul.

Speaking to the BBC on Tuesday, Mr Raab said he had spoken to all of the main third countries where the government expect people to flee and was "making sure we have got the practical arrangements to be able to identify those that are eligible so that they can get across the border".

Mr Raab could be pushed on the specifics of his contacts with countries in the region and whether any agreements have been put in place.

Why was the government's intelligence wrong?

Taliban patrols
EPA

The speed of the Taliban's advance to Kabul took many countries by surprise.

Mr Raab has acknowledged that the UK's assessment was "clearly wrong" but pointed out that other countries also failed to predict the pace at which the Afghan government would collapse.

He has also said intelligence gathering was not the Foreign Office's "lead responsibility"; however MPs will still want to know how the UK government got its assessment wrong.

Why were sensitive documents left in the UK embassy in Kabul?

Last week, The Times reported that documents with the contact details of Afghans working for - or applying to work for - the UK had been left behind at the British embassy in Kabul after staff evacuated the building.

It came as a UN report warned that the Taliban had been conducting door-to-door searches to find and threaten people who had worked for Nato forces or the previous Afghan government.

The Foreign Office insisted "every effort" was made to destroy sensitive embassy papers and that it had helped three of the affected families to safety.

MPs may seek assurances that others whose details were left behind have been offered help.

Should Mr Raab have returned from holiday sooner?

Earlier this month, Mr Raab faced criticism for being on holiday as the Taliban advanced on Kabul.

He has denied reports he was asked to return to the UK on 13 August but instead chose to remain abroad until 15 August.

Mr Raab subsequently admitted that "with hindsight" he would not have gone away, but dismissed suggestions he was "lounging on the beach" as nonsense, saying he was focused on the evacuation operation and the stability of Kabul airport.

Has the retreat from Afghanistan left the UK diminished and at greater risk than before?

Brize Norton airport
PA Media

The decision to end the foreign involvement in Afghanistan was made by President Joe Biden.

The UK had no part in it. Boris Johnson's government was not even able to get the US to extend the airlift by a few days, and it couldn't assemble a group of other countries that could keep the airport open.

So MPs may want to know if this leaves the UK looking like a weaker power, unable to act independently if the US isn't involved.

And what about the threat that extremists will again have a haven in Afghanistan?

The Taliban's links with al-Qaeda are well known, it still has groups listed by the US as terrorist organisations in its ranks today and there are others, such as IS-K, now at large in Afghanistan too.

So MPs may want to know what the UK will realistically be able to do, to try to prevent new security threats emerging in the region now UK forces have had to leave, the UK's allies have been defeated, the UK has no bases in neighbouring countries, and no official relationship with Afghanistan's new rulers.

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2021-08-31 23:07:59Z
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'Life-saving' twice-yearly injections can replace daily statin tablets for thousands - Daily Mail

Statins in a jab: 'Life-saving' twice-yearly injections can replace daily tablets for thousands of patients after approval by watchdog

  • National Institute for Health and Care Excellence approved cholesterol-lowering jabs
  • Hundreds of thousands will receive the jabs from their GP twice a year
  • The drug treatment cuts levels of 'bad' LDL cholesterol by around 50 per cent

Hundreds of thousands of people will receive cholesterol-lowering jabs from their GP twice a year as an alternative to statins, it was announced today.

The ‘game-changing’ treatment, called inclisiran, is now rolled out on the NHS after it was approved by the UK’s medical watchdog.

The drug cuts levels of ‘bad’ LDL cholesterol – a fatty substance which collects in blood vessels – by about 50 per cent, making it as effective as high-dose statins. It is delivered by injection once every six months, saving patients the need to take daily statin tablets.

The National Institute for Health and Care Excellence (Nice) has initially approved the jab only for patients with high cholesterol who already have heart disease or have had a heart attack or stroke – about 300,000 in total.

Hundreds of thousands of people will receive cholesterol-lowering jabs from their GP twice a year as an alternative to statins, it was announced today (stock image)

Hundreds of thousands of people will receive cholesterol-lowering jabs from their GP twice a year as an alternative to statins, it was announced today (stock image)

Experts claimed it will save around 30,000 lives and prevent 55,000 heart attacks and strokes within the next decade.

Health Secretary Sajid Javid said the ‘life-saving’ treatment was a ‘huge step forward in tackling the scourge of heart disease’. Patients will be injected by nurses at GP surgeries across England, with a second dose three months later and then injections twice a year. Inclisiran is more effective if taken alongside statins – but it can be used on its own for those who do not tolerate the pills.

Research is ongoing to see if the drug could be used on a preventative basis to benefit millions who are at risk of heart problems.

High cholesterol affects around two in five adults and is a major cause of heart disease, which is responsible for one in four deaths in England.

Some 8million adults in the UK are prescribed statins – but some are put off by its side effects, such as headaches and the hassle of taking a pill every day.

Inclisiran is the first convenient and effective alternative to the pills. The drug helps the liver remove cholesterol from the blood by blocking the production of a protein called PCSK9 which reduces the organ’s ability to remove cholesterol.

Health Secretary Sajid Javid said the ¿life-saving¿ treatment was a ¿huge step forward in tackling the scourge of heart disease¿

Health Secretary Sajid Javid said the ‘life-saving’ treatment was a ‘huge step forward in tackling the scourge of heart disease’

Inclisiran is usually sold for nearly £2,000 per dose, meaning it would cost around £4,000 a year per patient. But NHS England said it had negotiated a confidential ‘world-leading’ deal with the manufacturer Novartis, and 300,000 patients will receive the drug over the next three years. Statins cost around £20 a year per patient.

NHS boss Amanda Pritchard said the deal will ‘enable hundreds of thousands of people to benefit from this revolutionary treatment, while also being fair to taxpayers’.

Meindert Boysen, deputy chief executive of Nice, said: ‘Inclisiran represents a potential game-changer in preventing thousands of people from dying prematurely from heart attacks and strokes.’

Professor Kausik Ray, from Imperial College London, who led research into the drug, said: ‘It’s great news for patients. It will reduce their medication burden and offer convenience.’

Working women heart risk 

The trend towards more full-time working among women may have raised their risk of heart attack and stroke, a Swiss study has suggested.

Stress, sleep disorders and fatigue have risen at an ‘alarming’ rate among this group in recent decades, experts warn.

These factors contribute to cardiovascular disease, alongside smoking, high blood pressure and high cholesterol. Scientists from the University of Zurich analysed data on 22,000 men and women from 2007, 2012 and 2017 as the number of women working full-time rose from 39 to 44 per cent.

Meanwhile, those suffering work stress rose from 59 per cent in 2012 to 66 per cent in 2017 with the increases bigger in women. The results will be shown at the European Stroke Organisation Conference.

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2021-08-31 23:01:06Z
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