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The head of the European Medicines Agency (EMA) has said it is "increasingly difficult" to say there is "no cause and effect relationship" between the Oxford-AstraZeneca jab and "rare cases of unusual blood clots".
However, Marco Cavaleri, head of vaccine strategy at the EMA, told an Italian newspaper that full evaluation work was still "far from being completed" and that the risk-benefit ratio was still in favour of the vaccine.
He added: "We are a regulatory agency and we must have very precise data on the risk-benefit ratio.
"We are trying to get the precise picture of what is happening, to define in detail this syndrome due to the vaccine."
The UK's Medicines and Healthcare Products Regulatory Agency (MHRA) confirmed that of those 30 people, seven had died as of 24 March.
More from Covid
The UK regulator has maintained there is no evidence to suggest a casual link between blood clots and the Oxford jab, and that the benefits continue to outweigh any risk.
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Boris Johnson says people should follow the advice of the MHRA with regards to the AstraZeneca jab
But, when asked if the incidence of rare blood clots can be linked directly to the vaccine, Mr Cavaleri replied: "In my opinion we can now say it - it is clear there is an association with the vaccine.
"What causes this reaction, however, we still do not know".
"In summary: in the next few hours we will say the connection exists, but we still have to understand how this happens."
Mr Cavaleri confirmed the benefits of having the vaccination still outweighed the risks and added: "We will go into the various age groups in more detail. Young women, often protagonists of thrombosis cases, suffer less from the effect of COVID.
"We will therefore have to evaluate the risk-benefit ratio for them. Not forgetting that even young women end up in intensive care for COVID.
"Therefore, very meticulous work will be needed to understand if the risk-benefit ratio is in favour of the vaccine for all ages ".
An EMA spokesperson told Sky News that "PRAC, our safety committee, is meeting this week and is discussing the issue.
"We will inform upon the conclusion of the discussion."
Looking at the use of domestic COVID passports for people attending pubs and restaurants is "only the right thing to do", the vaccines minister has told Sky News.
Nadhim Zahawi admitted that requiring people to show certification before entering some venues "does throw up a number of difficult, ethical questions".
But he stressed the government would push on with piloting a COVID passport scheme at events such as the FA Cup final, as he suggested it would be "completely remiss and irresponsible" of ministers not to trial proposals.
Mr Zahawi confirmed people attending pubs and restaurants this month and next month - when allowed under stages two and three of the government's roadmap for easing lockdown restrictions - would not be required to show certification.
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On 12 April, pubs and restaurants will be able to serve people outdoors, while indoor serving is set to resume from 17 May.
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But Mr Zahawi also defended the government's decision to keep open the possibility of COVID passports - based on whether someone tests negative, has been vaccinated or has immunity after recovering from the disease - being more widely used later this year.
"For international travel, if our citizens need to travel at the right time when - obviously - international travel returns, we will make sure they're able to demonstrate their certification," he said.
"Whether it be a pre-departure test certificate or a vaccination test certificate.
"Domestically, step two we're coming up to and step three, there will absolutely no issue around pubs or restaurants requiring any form of certification.
"But it's only responsible as we see how this virus behaves, as we see how other countries are utilising technologies to make sure they keep the virus under control, then we should look at the same thing.
"It's only the right thing to do, we're all working towards the same outcome, which is to get our lives back, get our economy back up and running."
The government has been conducting a review into COVID certification - led by Cabinet Office minister Michael Gove - over the past few weeks.
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'No convincing answers' on vaccine passports
In a document published on Monday night, it was stated that ministers believe there are some settings - such as public transport and supermarkets - where people "should never be required" to prove their COVID status.
However, the document added that COVID certification could play a role in other settings - such as hospitality, theatres, nightclubs, festivals or sports events.
Labour's shadow health secretary Jonathan Ashworth accused ministers of being "at sixes and sevens" on the issue of domestic COVID passports.
Image:Nadhim Zahawi has defended the government's position on so-called 'vaccine passports'. Pic: Matt Brown/Flickr
"The government just need to clear this up because they're creating confusion," he told Sky News.
"I do think it is discriminatory to say to somebody... that you cannot go into Next or H&M unless you produce your vaccination status on an app, unless you produce that digital ID card.
"I don't think that is fair. If ministers are saying that is not what the policy is, then they have to explain why does the policy document they produced last night permit that scenario?
"There's a lot of confusion out there - I just want ministers to be honest and straight with us and tell us exactly what their policy proposals are."
More than 70 MPs - including more than 40 Conservatives - have already formed a major cross-party campaign against the use of COVID passports within the UK.
Meanwhile, Labour leader Sir Keir Starmer has signalled his party could oppose the plans after he suggested the "British instinct" will be against the introduction of passports for venues such as pubs.
The growing backlash at Westminster suggests Prime Minister Boris Johnson - if he bows to demands to hold a parliamentary vote - could face a battle in trying to get plans for COVID certification through the House of Commons.
Asked about the possibility of a Commons vote on the issue, Mr Johnson told a news conference on Monday: "First of all we need to work out exactly what the proposal might be.
"But certainly if there is something to put to parliament I have no doubt that we will be doing that.".
Looking at the use of domestic COVID passports for people attending pubs and restaurants is "only the right thing to do", the vaccines minister has told Sky News.
Nadhim Zahawi admitted that requiring people to show certification before entering some venues "does throw up a number of difficult, ethical questions".
But he stressed the government would push on with piloting a COVID passport scheme at events such as the FA Cup final, as he suggested it would be "completely remiss and irresponsible" of ministers not to trial proposals.
Mr Zahawi confirmed people attending pubs and restaurants this month and next month - when allowed under stages two and three of the government's roadmap for easing lockdown restrictions - would not be required to show certification.
Advertisement
On 12 April, pubs and restaurants will be able to serve people outdoors, while indoor serving is set to resume from 17 May.
More from Covid-19
But Mr Zahawi also defended the government's decision to keep open the possibility of COVID passports - based on whether someone tests negative, has been vaccinated or has immunity after recovering from the disease - being more widely used later this year.
"For international travel, if our citizens need to travel at the right time when - obviously - international travel returns, we will make sure they're able to demonstrate their certification," he said.
"Whether it be a pre-departure test certificate or a vaccination test certificate.
"Domestically, step two we're coming up to and step three, there will absolutely no issue around pubs or restaurants requiring any form of certification.
"But it's only responsible as we see how this virus behaves, as we see how other countries are utilising technologies to make sure they keep the virus under control, then we should look at the same thing.
"It's only the right thing to do, we're all working towards the same outcome, which is to get our lives back, get our economy back up and running."
The government has been conducting a review into COVID certification - led by Cabinet Office minister Michael Gove - over the past few weeks.
Please use Chrome browser for a more accessible video player
'No convincing answers' on vaccine passports
In a document published on Monday night, it was stated that ministers believe there are some settings - such as public transport and supermarkets - where people "should never be required" to prove their COVID status.
However, the document added that COVID certification could play a role in other settings - such as hospitality, theatres, nightclubs, festivals or sports events.
Labour's shadow health secretary Jonathan Ashworth accused ministers of being "at sixes and sevens" on the issue of domestic COVID passports.
Image:Nadhim Zahawi has defended the government's position on so-called 'vaccine passports'. Pic: Matt Brown/Flickr
"The government just need to clear this up because they're creating confusion," he told Sky News.
"I do think it is discriminatory to say to somebody... that you cannot go into Next or H&M unless you produce your vaccination status on an app, unless you produce that digital ID card.
"I don't think that is fair. If ministers are saying that is not what the policy is, then they have to explain why does the policy document they produced last night permit that scenario?
"There's a lot of confusion out there - I just want ministers to be honest and straight with us and tell us exactly what their policy proposals are."
More than 70 MPs - including more than 40 Conservatives - have already formed a major cross-party campaign against the use of COVID passports within the UK.
Meanwhile, Labour leader Sir Keir Starmer has signalled his party could oppose the plans after he suggested the "British instinct" will be against the introduction of passports for venues such as pubs.
The growing backlash at Westminster suggests Prime Minister Boris Johnson - if he bows to demands to hold a parliamentary vote - could face a battle in trying to get plans for COVID certification through the House of Commons.
Asked about the possibility of a Commons vote on the issue, Mr Johnson told a news conference on Monday: "First of all we need to work out exactly what the proposal might be.
"But certainly if there is something to put to parliament I have no doubt that we will be doing that.".
