Sabtu, 02 Mei 2020

U.K. Virus Tests Surpass Target, but Britain’s Deaths May Overtake Italy’s - The New York Times

LONDON — For Britons looking to judge their government’s desperate response to the coronavirus pandemic, the verdict has increasingly come down to two numbers: 100,000, the number of tests that officials promised to conduct every day by the end of April; and 27,510, the latest death toll.

On Friday, there was good news and bad news in the numbers: The government announced it had exceeded its testing target, carrying out 122,347 tests on the last day of the month. But with 739 more people dying from the virus that same day, Britain was also poised to soon overtake Italy in a few days as the hardest hit country in Europe.

The fixation on numbers is understandable but misplaced, experts said. Just because Britain can carry out more than 100,000 tests a day does not mean it has built an effective testing and contact tracing program, which experts say is needed to avert another spike in infections if the government eases the lockdown.

And while there would be grim symbolism for Britain in passing Italy in the total deaths, drawing direct comparisons between any two countries is extremely difficult, given differences in population, demographics, population density, and how the authorities collect the statistics.

Still, Britain’s health secretary, Matt Hancock, trumpeted the achievement of 122,000 tests, a 10-fold increase from when he set the goal on April 2, a day after having emerged from isolation himself with symptoms of the virus.

He said the achievement had set the stage for an equally ambitious program of contact tracing — identifying people who have come into contact with an infected person so they can be also isolated, helping curtail the spread of the disease. Mr. Hancock said this program would eventually allow Britain to lift its lockdown and return to a semblance of normalcy.

“I knew it was an audacious goal, but we needed an audacious goal,” said a visibly relieved Mr. Hancock, for whom the target had become a personal crucible. “The challenge we still face is vast, but we are making real progress.”

There were some lingering questions over whether the government changed its policy for counting tests to make its target. While officials insisted they had not changed the rules, they acknowledged having counted more than 27,000 home test kits, and more than 12,000 tests sent to satellite testing centers, at the time they were mailed rather than when they were returned to labs, with results.

Regardless how many tests Britain has conducted, medical experts said the government had yet to build a contact-tracing operation to match its testing capacity. Drawing so much attention to the 100,000 number, critics said, was mostly a public-relations stunt.

“The number of people tested is meaningless,” said Dr. Bharat Pankhania, an expert in infectious diseases at the University of Exeter Medical School. “If you fail to deliver on contact tracing, then you are testing as a ceremony rather than as a way to contain and isolate the outbreak.”

Other experts, however, said there was merit to setting a numerical goal for testing, given Britain’s slow start. In March, officials decided to abandon testing and tracing in the general population in favor of testing only those people with symptoms serious enough to hospitalize them.

“When there is a political priority to do something, then it can happen,” said Professor Devi Sridhar, director of the global health governance program at the University of Edinburgh. “Now we need the same effort and priority given to tracing and isolation, as it goes in a package: test, trace, isolate.”

To some extent, the government is a victim of its penchant for using numbers to reassure the public it has a coherent plan. On March 19, in one of Prime Minister Boris Johnson’s early public statements on the crisis, he said that he believed the British people could send the virus “packing” within 12 weeks.

Since returning to work after his own near-fatal bout of Covid-19, the disease caused by the virus, Mr. Johnson has fastened onto another metric: the number of new infections stemming from a single case, which has fallen to below one throughout Britain, but which Mr. Johnson fears could spike again if he lifts the social distancing measures too abruptly.

Alongside the plan to ramp up testing, the government plans by mid-May to recruit around 18,000 people — including around 3,000 in the field — to conduct contact tracing. That is supposed to operate with a cellphone app that is being tested next week in one place, the Isle of Wight.

But so far, Downing Street has been unable to say how many of the 18,000 new employees have been recruited.

Mr. Johnson once set an objective of 250,000 tests a day, though the government now says that was conceived at a time when the search was on for an inexpensive and user-friendly antibody test, which would detect whether a person had been infected in the past. In fact, when it was announced, Mr. Hancock’s 100,000 target also included the possibility of counting antibody tests.

“Targets work when you have confidence that hitting them helps you in meeting your goal,” said Stewart Wood, an adviser to former Prime Minister Gordon Brown. “The problem with this type of targeting is it suggests a level of competence which is not backed up by the strategy.”

From the start, the government has publicly plotted the country’s death toll relative to its neighbors, a comparison that initially looked favorable for Britain. But that data came under scrutiny, since it was based on deaths in hospitals only, while France’s, for example, included fatalities in nursing homes, too.

When non-hospital deaths were recently added into the equation, Britain suddenly appeared headed for among the worst fatality numbers in Europe. That prompted the government to add yet another new chart — based on per capita death rates — which puts it behind Belgium, Spain and Italy.

As of Friday, Italy’s deaths totaled 28,236 — a number that excludes deaths in nursing homes. Its daily fatality rate has mostly declined over the last week, and was at 269 on Friday.

“You can see the shift in government messaging emerge, and the new line is the importance of data comparability,” said Sophia Gaston, director of the British Foreign Policy Group and a fellow at the London School of Economics.

“There is some truth in that,” she said, “but at the same time it is dealing with the realization that Britain is likely to come out of this with a rather ghastly report card.”

The government, Mr. Wood said, would have been better served by explaining the uncertainty over statistics from the start and by being more explicit about the lack of up-to-date figures on nursing home fatalities.

“The public would have understood that lack of certainty,” he said. “Instead, they have stuck with measures which everyone gradually has got to know are not quite right, and then had to shift, almost as a concession.”

Elisabetta Povoledo contributed reporting from Rome.

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2020-05-02 08:18:02Z
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Jumat, 01 Mei 2020

Coronavirus: Trial begins to see if plasma from COVID-19 survivors can fight the virus - The Loppy

A trial has begun to test if plasma rich in antibodies from the blood of those who have recovered from COVID-19 could be the key to fighting the virus.

Blood is taken from a volunteer’s arm and then returned to the body once the liquid, known as convalescent plasma, has been removed.

If it proves successful, seriously unwell patients would receive a transfusion of the fluid to help their body fight the virus.

After a virus, your plasma contains antibodies that are used to help fight infection
Image:
After a virus, a person’s plasma contains antibodies used to fight infection

As a doctor who recently lost a close colleague to the coronavirus, neonatologist Matt Nash was in no doubt about volunteering.

“Seeing someone who you work with, are very close with, and is a friend, going through it and then ultimately losing their battle, has been quite an impetus,” he said.

“When the call came though asking whether I wanted to give some plasma, it was an easy option… ‘yes, anything I can do to help’.”

The whole process takes 45 minutes and provides two units of the liquid which can be frozen for future use.

If effective, a scaled-up national programme would provide up to 10,000 units per week, enough for 5,000 patients.

Tom Congdon is afraid of needles but was determined to help.

“I don’t really like hospital, but this was fine,” he said.

“Once I got screened, tested for blood pressure and everything, they just stuck the needle in, which hurt a lot less than I thought, and just went and did it.”

Health Secretary Matt Hancock said thousands of patients could potentially benefit from the treatment in the future.

“The UK has world-leading life sciences and research sectors and I have every hope this treatment will be a major milestone in our fight against this disease,” he said.

But while Dr Bharat Pankhania, senior clinical lecturer at the University of Exeter, hopes it will work, he has concerns.

“This is a blood-borne product so we have got to be really careful about not causing any harm… There are things that can go wrong, such as introducing an infection or an allergic reaction,” he said.

“The other thing is, the sooner we can give it to the patients the better, so we have got to work out who’s going to need it and how we are going to give it to them earlier in their illness.”

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Donors have to have felt better for least 28 days before taking part in the trial. They should be aged 17 to 66 and not have had a heart condition or be recently pregnant.

Jo Toozs-Hobson’s immediate family all caught the virus and her doctor husband spent five days in hospital. She described taking part as a “no-brainer”.

“We have got all these people in intensive care and if the antibodies in the plasma can make a difference then we should all be doing everything we can and this is something I can do, so that’s why I’m here,” she said.

Convalescent plasma has already been used to treat infections like SARS.

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2020-05-02 05:00:57Z
52780757238290

Boy shot and man injured in east London - BBC News

A boy has been shot in east London, police have said.

Police found the boy, believed to be 11 years old, and a man injured at a property in Kerry Drive, Upminster, at about 21:30 BST.

The man, thought to be in his 40s, had cuts to his head but it unclear what had caused his injuries. The condition of the man and the boy is not known.

A number of people fled the scene before officers arrived. No arrests have been made.

Police are appealing for any witnesses to contact them.

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2020-05-02 03:47:26Z
52780760271433

Boy shot and man injured in east London - BBC News

Boy shot and man injured in east London - BBC News
Kerry Drive, Upminster

A boy has been shot in east London, police have said.

Police found the boy, believed to be 11 years old, and a man injured at a property in Kerry Drive, Upminster, at about 21:30 BST.

The man, thought to be in his 40s, had cuts to his head but it unclear what had caused his injuries. The condition of the man and the boy is not known.

A number of people fled the scene before officers arrived. No arrests have been made.

Police are appealing for any witnesses to contact them.


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2020-05-02 01:46:00Z
52780760271433

Boy, 11, shot and man found with head injuries in east London - Sky News

An 11-year-old boy has been shot in east London, police have said.

Officers found the boy and a man, believed to be in his 40s, suffering injuries after they were called to an address in Kerry Drive, Upminster, on Friday at around 9.30pm.

The man suffered cuts to his head. Police said they were not sure if his injuries were caused by the firearm discharge.

The condition of the man and the boy is not known.

Boy, 11, shot and man found with head injuries in Upmister, east London
Image: Police say a number of suspects fled the scene before officers arrived at the address

Police said: "A number of suspects had made off prior to the arrival of police.

"A police helicopter assisted officers in searches, however there has been no arrest at this stage."

Anyone who witnessed the incident or who has information that can assist the police are asked to call 101 quoting ref 7285/01may.

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2020-05-01 23:17:23Z
52780760271433

U.K. Virus Tests Surpass Target, but Britain’s Deaths May Overtake Italy’s - The New York Times

LONDON — For Britons looking to judge their government’s desperate response to the coronavirus pandemic, the verdict has increasingly come down to two numbers: 100,000, the number of tests that officials promised to conduct every day by the end of April; and 27,510, the latest death toll.

On Friday, there was good news and bad news in the numbers: The government announced it had exceeded its testing target, carrying out 122,347 tests on the last day of the month. But with 739 more people dying from the virus that same day, Britain was also poised to soon overtake Italy in a few days as the hardest hit country in Europe.

The fixation on numbers is understandable but misplaced, experts said. Just because Britain can carry out more than 100,000 tests a day does not mean it has built an effective testing and contact tracing program, which experts say is needed to avert another spike in infections if the government eases the lockdown.

And while there would be grim symbolism for Britain in passing Italy in the total deaths, drawing direct comparisons between any two countries is extremely difficult, given differences in population, demographics, population density, and how the authorities collect the statistics.

Still, Britain’s health secretary, Matt Hancock, trumpeted the achievement of 122,000 tests, a 10-fold increase from when he set the goal on April 2, a day after having emerged from isolation himself with symptoms of the virus.

He said the achievement had set the stage for an equally ambitious program of contact tracing — identifying people who have come into contact with an infected person so they can be also isolated, helping curtail the spread of the disease. Mr. Hancock said this program would eventually allow Britain to lift its lockdown and return to a semblance of normalcy.

“I knew it was an audacious goal, but we needed an audacious goal,” said a visibly relieved Mr. Hancock, for whom the target had become a personal crucible. “The challenge we still face is vast, but we are making real progress.”

There were some lingering questions over whether the government changed its policy for counting tests to make its target. While officials insisted they had not changed the rules, they acknowledged having counted more than 27,000 home test kits, and more than 12,000 tests sent to satellite testing centers, at the time they were mailed rather than when they were returned to labs, with results.

Regardless how many tests Britain has conducted, medical experts said the government had yet to build a contact-tracing operation to match its testing capacity. Drawing so much attention to the 100,000 number, critics said, was mostly a public-relations stunt.

“The number of people tested is meaningless,” said Dr. Bharat Pankhania, an expert in infectious diseases at the University of Exeter Medical School. “If you fail to deliver on contact tracing, then you are testing as a ceremony rather than as a way to contain and isolate the outbreak.”

Other experts, however, said there was merit to setting a numerical goal for testing, given Britain’s slow start. In March, officials decided to abandon testing and tracing in the general population in favor of testing only those people with symptoms serious enough to hospitalize them.

“When there is a political priority to do something, then it can happen,” said Professor Devi Sridhar, director of the global health governance program at the University of Edinburgh. “Now we need the same effort and priority given to tracing and isolation, as it goes in a package: test, trace, isolate.”

To some extent, the government is a victim of its penchant for using numbers to reassure the public it has a coherent plan. On March 19, in one of Prime Minister Boris Johnson’s early public statements on the crisis, he said that he believed the British people could send the virus “packing” within 12 weeks.

Since returning to work after his own near-fatal bout of Covid-19, the disease caused by the virus, Mr. Johnson has fastened onto another metric: the number of new infections stemming from a single case, which has fallen to below one throughout Britain, but which Mr. Johnson fears could spike again if he lifts the social distancing measures too abruptly.

Alongside the plan to ramp up testing, the government plans by mid-May to recruit around 18,000 people — including around 3,000 in the field — to conduct contact tracing. That is supposed to operate with a cellphone app that is being tested next week in one place, the Isle of Wight.

But so far, Downing Street has been unable to say how many of the 18,000 new employees have been recruited.

Mr. Johnson once set an objective of 250,000 tests a day, though the government now says that was conceived at a time when the search was on for an inexpensive and user-friendly antibody test, which would detect whether a person had been infected in the past. In fact, when it was announced, Mr. Hancock’s 100,000 target also included the possibility of counting antibody tests.

“Targets work when you have confidence that hitting them helps you in meeting your goal,” said Stewart Wood, an adviser to former Prime Minister Gordon Brown. “The problem with this type of targeting is it suggests a level of competence which is not backed up by the strategy.”

From the start, the government has publicly plotted the country’s death toll relative to its neighbors, a comparison that initially looked favorable for Britain. But that data came under scrutiny, since it was based on deaths in hospitals only, while France’s, for example, included fatalities in nursing homes, too.

When non-hospital deaths were recently added into the equation, Britain suddenly appeared headed for among the worst fatality numbers in Europe. That prompted the government to add yet another new chart — based on per capita death rates — which puts it behind Belgium, Spain and Italy.

As of Friday, Italy’s deaths totaled 28,236 — a number that excludes deaths in nursing homes. Its daily fatality rate has mostly declined over the last week, and was at 269 on Friday.

“You can see the shift in government messaging emerge, and the new line is the importance of data comparability,” said Sophia Gaston, director of the British Foreign Policy Group and a fellow at the London School of Economics.

“There is some truth in that,” she said, “but at the same time it is dealing with the realization that Britain is likely to come out of this with a rather ghastly report card.”

The government, Mr. Wood said, would have been better served by explaining the uncertainty over statistics from the start and by being more explicit about the lack of up-to-date figures on nursing home fatalities.

“The public would have understood that lack of certainty,” he said. “Instead, they have stuck with measures which everyone gradually has got to know are not quite right, and then had to shift, almost as a concession.”

Elisabetta Povoledo contributed reporting from Rome.

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2020-05-01 22:12:01Z
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Coronavirus: Fertility services to resume within a fortnight as UK passes virus peak - The Loppy

Fertility services will be able to resume in the UK within the next fortnight almost two months after treatments were halted by the coronavirus pandemic.

Announcing the decision on Friday, Health Secretary Matt Hancock said he was “delighted” and assured that strict guidelines would “ensure staff and patients remain safe”.

Clinics across the country can now apply to resume services from 11 May, according to the Human Fertilisation and Embryology Authority (HFEA), as long as safety and protection of staff and patients can be ensured.

Guidance for reopening is currently being drawn up by NHS England and NHS Clinical Commissioners, and will be given to all Clinical Commissioning Groups (CCGs) across the country.

Such requirements will include social distancing being observed in waiting rooms and personal protective equipment (PPE) being supplied.

Telephone appointments could also replace some face-to-face meetings, if suitable, while an auditing tool will ensure these measures are being followed.

Later this week, Mr Hancock is due to write to CCGs to find out if they will be able to restart treatment – whether through an NHS clinic or private service – “to ensure fair provision”.

It comes after the Department of Health and Social Care acknowledged that while private clinics may be able to reopen quickly, it may take a little longer for NHS services to reach the requirements stipulated in the guidelines due to staff being redeployed.

Speaking at the daily Downing Street coronavirus briefing, Mr Hancock said he understood “just how time-sensitive treatment can be and how important it is for the families affected”.

He added: “And I know that this treatment can change lives for the better forever.

“So when I say thank you for all of you, everybody watching, for staying at home to protect the NHS of course I’m saying thank you on behalf of the lives that you’re saving.

“But I’m also saying thanks on behalf of the lives that the NHS can now once again help to create.”

Meanwhile, Sally Cheshire, the chair of HFEA, said she was “pleased” that clinics would be able to apply to resume services, acknowledging that the closures have been “extremely distressing” for patients.

She added: “This will be good news for those wanting to resume treatment and have the opportunity to try for their much longed for family.”

Geeta Nargund, lead consultant for Reproductive Medicine at St George’s Hospital NHS Trust, said she was also “delighted” that services could soon be restarted.

She added: “We thank the government for recognising the distress faced by thousands of women and couples across our nation and acting swiftly to help them.

“We must ensure that effective social distancing and safety measures are put in place so that we can not only help save lives but start creating lives again.”

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2020-05-01 20:12:21Z
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