Minggu, 12 April 2020

Where Germany had success in fighting coronavirus, Britain stumbled - The Washington Post

Public health experts fear that Britain’s mortality rate may soon be or already is the highest in all of Europe, as pandemic-ravaged Italy and Spain slowly get to grips with the disease. Britain’s steady shift toward becoming the new European epicenter of the outbreak stands in stark contrast with nearby Germany, the only country on the continent with a bigger economy and whose government reported its first case around the same time as Johnson’s government.

In the second week of March, Johnson’s government justified its largely lax strategy — schools, restaurants and other major venues remained open, while only the elderly who were already infirm were advised to stay home — on the grounds that it was pursuing “herd immunity,” counting on Britain’s invulnerable groups to contract the disease and become immune. Just days later, the government backtracked, its supposed pragmatism crashing against new worrying projections of hundreds of thousands of deaths should it not impose lockdowns and strict measures of social distancing.

Meanwhile, on March 11, German Chancellor Angela Merkel warned that 60 to 70 percent of her country could contract the virus. But that wasn’t a statement of resignation — Merkel said the challenge now was all about winning time, and her country’s federal, state and local authorities had already set about attempting to achieve that.

“Nearly three months since their first positive cases, Germany has conducted more than 1.3 million tests and contact tracing remains central to its strategy,” noted BuzzFeed in a piece that presented a thorough timeline comparing both countries’ handling of the crisis. “The UK has carried out fewer than 335,000 tests and all but dropped attempts to aggressively trace contacts. About 3,000 people have died so far in Germany. More than 10,000 have died in the UK.”

Emily Haber, the German ambassador to the United States, waved away any notion of German exceptionalism amid the pandemic. “We can’t state there is a specific German template,” she said during an online briefing call last week with reporters organized by the Meridian International Center in Washington.

Haber pointed to a number of key factors that gave Germany an advantage in its preparations: the widespread mass testing program; a relatively young population that made up the initial bulk of covid-19 cases, and mostly survived; and the benefit of time to expand intensive care facilities and build up stockpiles of medical equipment.

“We were able to prepare because we were not the first country in Europe affected, and we saw and could analyze developments elsewhere,” Haber said, adding that the “well-oiled machinery” of the country’s universal health-care system and effective coordination between the federal government and local and state agencies helped. Germany’s hospitals still have a surfeit of available beds for coronavirus-positive patients and may not face the same pressures that buckled health-care systems in other European countries.

Compared with Britain, Germany gave itself a real head start in testing. “The people [they were in contact with] were also traced and tested repeatedly and they were isolated as well,” Evangelos Kotsopoulos, spokesman for the German Association of Accredited Laboratories, told the BBC, adding that it helped “flatten the curve a bit and slowed down the rate of infection.”

“Rather than following countries like South Korea in taking immediate draconian action to stop the disease — including the use of mass testing — Johnson’s team thought a more modulated approach would ultimately save more lives and cause less economic harm,” the Financial Times detailed in a piece on the government’s early missteps.

Now, Britain finds itself playing catch-up while lacking key German advantages: a sophisticated and sizable biotech industry that helped fast-track widespread testing, and a decentralized political structure that — unlike, say, its equivalent in the United States — effectively enabled private laboratories and local and state-level agencies to take the lead on implementing testing. “While Germany broadened its testing strategy to cover all those with mild symptoms — the core of a strategy to test, trace and isolate people infected with the virus — by March, Britain was struggling to scale up,” the FT noted.

“We have the best scientific labs in the world but we did not have the scale,” British Health Secretary Matt Hancock told the BBC. “My German counterpart, for instance, could call upon 100 testing labs ready and waiting when the crisis struck, thanks in large part to Roche, one of the biggest diagnostic companies in the world.”

As Johnson continues his recovery, he faces an altogether different national challenge in 2020 than the one he had set out to achieve: Brexit. “The pandemic may yet prove to be this calamity. Perhaps history or the electorate will judge him for not taking it seriously enough, for acting too slowly or too reluctantly,” the Atlantic’s Tom McTague wrote in an essay that touched on the “sense of destiny” that seemed to tail the prime minister’s political career.

McTague added: Johnson’s “sudden deterioration came just as things in the country at large were getting worse. Johnson had not been laid low saving the day like Horatio Nelson, leading Britain through its modern-day Battle of Trafalgar. Instead, he appeared to be living the crisis itself.”

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2020-04-13 04:49:47Z
CAIiEOOZcS8sErnAdEHpfqZuKbwqGAgEKg8IACoHCAowjtSUCjC30XQwzqe5AQ

Britain at its best in a crisis, says Prince William - Page Six

LONDON – Prince William has said Britain is at its best in a crisis, his office said on Sunday, the latest in a series of messages from the royal family seeking to galvanise the nation during the coronavirus pandemic.

Queen Elizabeth has twice addressed Britons in the past week, while heir-to-the-throne Prince Charles, who tested positive for the new virus, has also issued several video and audio messages since he recovered.

William’s message came on a day when the COVID-19 death toll in hospitals across the United Kingdom passed 10,000.

“I think Britain is at its best when faced with a crisis,” the queen’s grandson said during a call with a community charity in northern England that runs a food bank and has been delivering hot meals to isolated people.

“We all pull together and that community spirit comes rushing back quicker than anything else,” William said on the call, according to his office at Kensington Palace.

William, who is second-in-line to the throne after his father Charles, has become the patron of the National Emergencies Trust (NET) for 2020, the palace said.

Created in 2019, the NET seeks to coordinate with not-for-profit organizations to direct public donations to specific appeals and to distribute funds fairly and efficiently.

The NET’s Coronavirus Appeal in March, launched by William in March, has raised millions of pounds.

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2020-04-12 21:41:44Z
52780723492616

UK cancels order for simple ventilators, needs more complex ones: source - Reuters

LONDON (Reuters) - Britain has cancelled an order for thousands of units of a simple model of ventilator developed by industrial companies to treat COVID-19 because more sophisticated devices are now needed, a source involved in the project said on Sunday.

FILE PHOTO: Medical staff are seen outside the NHS Nightingale Hospital at the Excel Centre in London as the spread of the coronavirus disease (COVID-19) continues, London, Britain, April 11, 2020. REUTERS/Henry Nicholls

The government confirmed it no longer required that particular model, known as BlueSky.

“We are no longer supporting the production of the BlueSky device following a reassessment of the product’s viability in light of the ever developing picture around what is needed to most effectively treat COVID-19,” said a spokesman for the Cabinet Office, which is coordinating ventilator orders.

“We are continuing to work at unprecedented speed with a number of other manufacturers to scale up UK production of ventilators,” the spokesman said.

The government has appealed to industry to come forward with new models of ventilator that could be produced on a large scale at short notice to help the National Health Service deal with a surge in patients infected with the new coronavirus.

More than 30,000 ventilators in total have been ordered from various consortia of firms from sectors including aerospace, engineering and Formula One.

The source, who did not wish to be named because they were not authorised to disclose sensitive details to the media, said the group involved in the BlueSky project had been preparing to deliver thousands of units.

The source said the reason given by the government to the BlueSky team for cancelling the order was that while the overall number of new UK coronavirus infections was slowing, cases seen in hospitals were more complex than expected.

With several projects competing for the same components, which are in limited supply, the government decided to prioritise more sophisticated devices and cancel the BlueSky order with immediate effect, the source said.

The government is going ahead with the production and delivery of other devices as part of its initiative with industry. The first paraPac devices from Smiths Group were delivered to hospitals on Sunday.

Other devices are currently going through testing, including newly designed products. The government has said it will confirm orders once the new devices pass approvals and have confirmed delivery schedules.

Reporting by London Bureau; Writing by Estelle Shirbon; Editing by Giles Elgood

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2020-04-12 21:35:00Z
CAIiEGfrBXD0uSzh4JLdHBHVMUUqFggEKg0IACoGCAowt6AMMLAmMIT6lwM

U.K. Prime Minister Boris Johnson Released From Hospital - The Wall Street Journal

U.K. Prime Minister Boris Johnson recorded a message for the public on Sunday after leaving St. Thomas’s hospital in London after treatment for Covid-19. Photo: Pippa Fowles/10 Downing Street

U.K. Prime Minister Boris Johnson has left the hospital and is continuing to recover from coronavirus, as recorded deaths from the illness across Britain and Northern Ireland passed the 10,000 mark.

Mr. Johnson, 55, will spend some time at Chequers, the country residence of British prime ministers, as his government begins to assess when and how to ease the lockdown restrictions introduced to limit the spread of the infection, or whether to extend them.

“On the advice of his medical team, the P.M. will not be immediately returning to work,” a spokesman said.

In a video message released after his discharge, Mr. Johnson thanked the staff of Britain’s National Health Service, or NHS, for saving his life after he was admitted to St. Thomas’ Hospital in London on April 5, mentioning doctors and nurses by name. He urged people to continue practicing social distancing and stay home whenever possible to ease the burden on the country’s health-care system.

“Because although we mourn every day those who are taken from us in such numbers and though the struggle is by no means over, we are now making progress in this incredible national battle against coronavirus—a fight we never picked against an enemy we still don’t entirely understand,” Mr. Johnson said. “We are making progress in this national battle because the British people formed a human shield around this country’s greatest national asset, our National Health Service.”

He initially had tried to shake off the symptoms of Covid-19, the disease caused by the new coronavirus, while isolating himself in his apartment at No. 10 Downing Street, but his condition quickly deteriorated. News he had been taken into intensive care and administered oxygen to help ease his breathing fanned worries about the dangers posed by the virus.

Carrie Symonds, Mr. Johnson’s fiancée, with whom he is expecting a child, said she owed a debt of gratitude to the staff of the NHS that she would never be able to repay.

Mr. Johnson moved to Chequers, the country residence of Britain's prime minister.

Photo: Catherine Ivill/Getty Images

“There were times last week that were very dark indeed,” she said on her verified account on Twitter. “My heart goes out to all those in similar situations, worried sick about our loved ones.”

The severity of Mr. Johnson’s illness raised the prospect of a power vacuum as Britain approached the worst of the unprecedented public-health crisis.

In addition to testing the resilience of Britain’s state health-care service, the pandemic also prompted the government to instruct millions of citizens to stay at home, badly disrupting the economy and presenting the challenge of how to restart it once the spread of the virus is considered to be under control.

The U.K. Treasury said Thursday it plans to dip into an overdraft facility at the Bank of England to help finance spending, a sign the government’s need for cash is rising as it pumps money to stricken businesses and households.

British officials Sunday said the death toll from Covid-19 had passed 10,000 to reach 10,612 after 737 additional people were reported to have died. The figures don’t include deaths outside of hospitals, out in the community or in facilities such as care homes. Matt Hancock, Britain’s health secretary, told a news briefing there are signs that the numbers of fresh infections and hospitalizations were beginning to flatten, but people should continue practicing social distancing to prevent further infections.

Police officers outside of St Thomas' Hospital after Mr. Johnson was moved to intensive care on April 6.

Photo: henry nicholls/Reuters

“The future of this virus is unknown,” Mr. Hancock said.

The lockdown, in which people are encouraged to stay home except for essential tasks or brief exercise, will remain in place at least until the end of this week, when officials are scheduled to discuss the matter, and likely for longer to slow the spread of the virus, officials have said.

Britain’s informal code of government doesn’t designate a vice prime minister who automatically takes charge when the leader is incapacitated. On falling ill, Mr. Johnson handed those duties to Foreign Secretary Dominic Raab, who is expected to continue the role until the prime minister has recovered further.

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The British government has been criticized by opposition parties and some medical experts for an unorthodox strategy to address the coronavirus. They say it waited too long to impose stringent social-distancing measures.

Mr. Johnson’s government has also been criticized for not mass testing people to identify potential carriers and those who have contracted the virus but have recovered and are now immune.

Write to James Hookway at james.hookway@wsj.com

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2020-04-12 17:32:01Z
CAIiECjApjwpSpaqq3tXZ-iVFvEqGAgEKg8IACoHCAow1tzJATDnyxUww8rPBg

Coronavirus ‘Immunity Passport’ Stumbles in U.K. - The Wall Street Journal

Chris Whitty, the U.K.’s chief medical officer, says ‘we’re feeling our way to some extent’ in trying to develop immunity tests.

Photo: Victoria Jones/Zuma Press

The British government has touted “immunity passports” as a near-term way of loosening the coronavirus-inspired lockdown that is threatening to bring the U.K.’s economy to a standstill. Rolling them out is proving complicated.

The effort would rely on testing to identify those who have contracted and recovered from the disease caused by the new virus, by identifying specific antibodies—tailor-made proteins produced by the body to neutralize viruses and other invaders—in the blood.

These antibody tests are different from the swab tests aimed at determining whether a person carries the virus. They are the same as the ones being rolled out in many countries, including in the U.S., as part of long-term campaigns aimed at determining what proportion of the population has been infected by the new coronavirus, and gauging immunity at a national level.

In the U.K., however, officials have proposed using them at an individual level, to provide people assurances that they can leave lockdown without risk of contracting the disease, known as Covid-19.

The prospect is tantalizing. Immune workers could return to jobs. Health-care employees could go to work without fear of contracting the virus from the newly infected. People could visit elderly relatives again, confident they wouldn’t pass on the virus.

Other countries, including the U.S., also are considering the use of immunity passports. “This is something that’s being discussed,” Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases and a member of the White House Coronavirus Task Force, told CNN. “It might actually have some merit under certain circumstances.”

But antibody tests are challenging to develop.

A growing number of hospitals are investigating antibody testing and blood-plasma therapy as a way to combat the new coronavirus in sick patients. WSJ’s Daniela Hernandez explains. Photo illustration: Laura Kammermann

An accurate test must detect an antibody that is unique to SARS-CoV-2, the virus that causes the disease. The immune system produces a medley of antibodies in response to any pathogen, some of which may also be deployed in fending off closely related viruses. A test that picked up one of those would produce false-positive results, and risk sending someone back to work who wasn’t immune.

Once the right antibody has been identified, biologists also must ensure that it is potent enough to beat a future encounter with the virus.

“For the coronavirus, it is still difficult to answer that question,” said Bernard Binetruy, a research director with French medical institute Inserm.

Testing the Tests

Scientists are developing tests to detect antibodies from Covid-19, potentially signaling immunity. Here is how those tests might work if they succeed.

Doctors and scientists say they hope that antibodies will provide a degree of immunity against the coronavirus but caution that they need more time to assess what concentration is necessary and how long any protection will last.

“Even if people know they’ve had the virus, we have no idea how long the immunity will last,” said Louise Cosby, a professor of microbiology at Queen’s University Belfast. “Everybody’s operating with a lack of knowledge.”

Another issue is that in countries that have imposed lockdowns to limit the spread of the virus, the number of people with effective immunity—and therefore who could be eligible for immunity certificates—might be limited.

Jean-François Delfraissy, a doctor and immunology specialist who leads a scientific board advising the French government on how to tackle the pandemic, said he has cooled on the idea of immunity passports because of growing uncertainties on the duration of antibody protection, and because preliminary data he has received from China, Italy, and parts of France showed that immunity stood at only about 10%.

“Two weeks ago, I thought that we would be able to separate the French population in two groups,” he said. “Now I say, ‘beware, beware,’ we still have many things to learn.”

In Britain, politicians recently dangled the possibility of immunity testing, after buying millions of antibody tests from various suppliers in Southeast Asia. The hope was that they could start rolling out the tests within weeks, starting with health-care workers. But officials have now retreated from that promise after scientists found the tests weren’t reliable enough.

“Inevitably, we’re feeling our way to some extent,” said Chris Whitty, the U.K.’s chief medical officer, at a news briefing last week.

Experts say it will take at least another month, and probably longer, for any antibody test to perform well enough for a mass rollout. The government is calling on businesses to help speed progress.

AstraZeneca PLC, one of Britain’s biggest drugmakers, has started work on developing a reliable at-home antibody test that could be used to check for immunity, said Mene Pangalos, the company’s executive vice president for biopharmaceutical research and development. The challenge is to overcome problems associated with existing products, which yield high false-positive and false-negative rates, he said.

Some doctors cautioned that at-home tests would at best provide an indication that will necessitate subsequent in-lab tests for confirmation.

SHARE YOUR THOUGHTS

If you had tested positive for the new coronavirus, would you feel safe coming in close contact with others who are still infected? Why, or why not? Join the conversation below.

In France, Paris Mayor Anne Hidalgo has said that immunity passports should be put in place to help ease the lockdown. The military has ordered individual tests from a local provider, and one lab, Atoutbio, has begun conducting antibody tests relying on equipment from China. Health authorities said it was too early to use any results to issue immunity passes.

In Italy, one of the countries hit hardest by the coronavirus pandemic, the region of Veneto has floated the idea of issuing immunity certificates, but national health authorities also warned that more work was needed. “So far, the serologic tests we have assessed aren’t entirely satisfactory, meaning that their sensitivity wasn’t of 100%, but well below 100%,” said Giovanni Rezza, head of infectious diseases at the National Health Institute in Rome.

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Write to Denise Roland at Denise.Roland@wsj.com and David Gauthier-Villars at David.Gauthier-Villars@wsj.com

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2020-04-12 16:46:50Z
CAIiELbWUoNRX_gVVMDzQ_8fY-IqGAgEKg8IACoHCAow1tzJATDnyxUwxMrPBg

In video message, UK's Johnson says medics saved his life - Reuters

LONDON (Reuters) - British Prime Minister Boris Johnson left hospital on Sunday and thanked the National Health Service for saving his life, saying “things could have gone either way” for him as he battled COVID-19.

British Prime Minister Boris Johnson delivers a speech to British citizens after being discharged from hospital, in London, Britain, April 12, 2020 in this screen grab taken from social media video. Twitter/@BorisJohnson via REUTERS

Johnson, 55, was taken to St Thomas’ Hospital in central London on April 5, suffering from persistent symptoms of the disease caused by the new coronavirus. On April 6 he was moved into intensive care, where he remained until April 9.

“I have today left hospital after a week in which the NHS has saved my life, no question,” he said in a five-minute video message posted on Twitter from 10 Downing Street as the official death toll in Britain passed 10,000.

He named and thanked the nurses who had cared for him, with a special mention for two of them, Jenny from New Zealand and Luis from Portugal, who he said had stood by his bedside for 48 hours “when things could have gone either way”.

“The reason in the end my body did start to get enough oxygen was because for every second of the night they were watching and they were thinking and they were caring and making the interventions I needed,” he said.

Johnson wore a suit and tie and spoke in his usual energetic manner. In characteristic fashion, he made a joke, thanking the doctors who had cared for him, “several of them for some reason called Nick”.

Johnson will continue his recovery at Chequers, the official prime ministerial country residence northwest of London, his office said.

A Reuters photographer saw Johnson and his pregnant fiancee Carrie Symonds, 32, who has also suffered from COVID-19 symptoms, being driven out of Downing Street, in central London, with their dog.

“There were times last week that were very dark indeed. My heart goes out to all those in similar situations, worried sick about their loved ones,” Symonds said on Twitter. “Today I’m feeling incredibly lucky.”

While Johnson has been out of action, his ministers have come under mounting pressure to explain why the national death toll is rising so fast.

Britain has reported two days in a row of hospital deaths increasing by more than 900 people. Friday’s death toll of 980 surpassed the highest recorded in a single day in Italy, the hardest hit country in Europe so far.

The death toll in Britain rose to 10,612, an officials statement said on Sunday.

Johnson thanked the public for following strict social distancing guidelines in place since March 23 and assured them their efforts were paying off.

“I want you to know that this Easter Sunday I do believe that your efforts are worth it, and are daily proving their worth,” he said.

“Because although we mourn every day those who are taken from us in such numbers, and though the struggle is by no means over, we are now making progress in this incredible national battle against coronavirus.”

Editing by Alison Williams and Giles Elgood

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2020-04-12 15:13:00Z
52780718853831

British PM Johnson discharged from hospital after coronavirus treatment - Reuters

LONDON (Reuters) - Prime Minister Boris Johnson said he owed his life to hospital staff, in his first comments since leaving intensive care for coronavirus treatment, while his government came under mounting pressure to explain why the death toll was rising so fast.

FILE PHOTO: Britain's Prime Minister Boris Johnson leaves Downing Street, as the spread of coronavirus disease (COVID-19) continues. London, Britain, March 25, 2020. REUTERS/Hannah Mckay/File Photo

Britain has reported two days in a row of hospital deaths increasing by more than 900 people. Friday’s death toll of 980 surpassed the highest recorded in a single day in Italy, the hardest hit country in Europe so far.

The British government has had to defend its response, which has included carrying out far less testing than in some other European countries and ordering a lockdown that came comparatively late. Ministers have also resisted apologising for a shortage of protective gear for hospital staff.

Johnson, 55, was taken to St Thomas’s Hospital in central London on April 5, suffering from persistent symptoms of the disease caused by the new coronavirus. On April 6 he was moved into intensive care, where he remained until April 9.

“I can’t thank them enough. I owe them my life,” Johnson said of the staff of Britain’s state-run National Health Service at the hospital, in his first comments since being moved back to a regular ward. The comments were released to journalists and confirmed by his office on Sunday.

His Downing Street office said Johnson “continues to make very good progress”. In his absence, Foreign Secretary Dominic Raab is deputising for him.

In a sign of the gravity of the emergency, Queen Elizabeth issued her second rallying message in a week, telling the nation that “coronavirus will not overcome us”.

Archbishop of Canterbury Justin Welby, spiritual leader of the worldwide Anglican communion, delivered an Easter Sunday sermon from the kitchen of his London flat, recorded on his computer tablet.

“WE DO HAVE A PLAN”

Meanwhile, ministers were facing uncomfortable questions about whether the alarming rise in the death toll was due to the relatively late decision to impose a lockdown on March 23.

“Well, different countries have different cycles in terms of where they are in terms of the spread of this pandemic,” business minister Alok Sharma told Sky News on Sunday when asked to explain the reason for the poor UK numbers.

Health minister Matt Hancock suggested during a BBC radio interview on Saturday that Britain’s daily death toll had exceeded Italy’s because it had a bigger population. The UK population is about 66 million while Italy’s is 60 million.

When asked why Germany, with a population of about 83 million, had much lower numbers, he said: “The German situation is one I look at a lot.”

Ministers have insisted that the government took the right steps at the right time, guided by scientific advice.

NHS doctors and nurses across the country are complaining about a lack of personal protective equipment (PPE). About 20 frontline medical staff are reported to have died of the disease after treating patients.

Asked on Sunday whether he would apologise over the loss of life in the NHS and the lack of PPE, Sharma replied: “I said I was sorry for the loss of any life in this pandemic but we are facing an unprecedented situation.

FILE PHOTO: A sign of support for British Prime Minister Boris Johnson, who has been in hospital since Monday as the spread of the coronavirus disease (COVID-19) continues, in Swynnerton, Britain, April 9, 2020. REUTERS/Carl Recine/File Photo

“We do have a plan, we are putting that in place, we’re making sure that there are millions of PPE kits going out to the frontline, and of course we need to be doing even more.”

The new leader of the opposition Labour Party, Keir Starmer, said the government should acknowledge failings more openly.

“I think it would be smart of the government to acknowledge that their ambition for the equipment to be where it should be ... isn’t being matched and probably just apologise for that and get on with it,” he told Sky News.

Reporting by Estelle Shirbon; Editing by Peter Graff

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https://news.google.com/__i/rss/rd/articles/CBMinQFodHRwczovL3d3dy5yZXV0ZXJzLmNvbS9hcnRpY2xlL3VzLWhlYWx0aC1jb3JvbmF2aXJ1cy1icml0YWluL3BtLWpvaG5zb24tc2F5cy1oZS1vd2VzLW1lZGljcy1oaXMtbGlmZS1hcy1hbGFybS1ncm93cy1vdmVyLXNvYXJpbmctdWstZGVhdGgtdG9sbC1pZFVTS0NOMjFVMDZX0gE0aHR0cHM6Ly9tb2JpbGUucmV1dGVycy5jb20vYXJ0aWNsZS9hbXAvaWRVU0tDTjIxVTA2Vw?oc=5

2020-04-12 14:45:12Z
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